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The only side effect reported by the subjects taking 5-HTP was stomachache, of which there were 41 instances during the entire three-year trial. In the placebo group, there were only 10 instances of stomachache, but also 118 instances of nausea and 78 of abdominal pain. This is not inconsistent with the very few side effects other studies have reported by those taking 5-HTP. These results may be explained by 5-HTP's ability to reduce hypersensitivity to pain. Moreover, in the study, eosinophilia (elevation of the special white blood cells associated with inflammation) was not reported in the 5-HTP group; in the control group, there was one case.
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